24 seconds: Early administration of thrombopoietin in rats following experimental stroke minimizes cognitive functioning impairments. Rats underwent middle cerebral artery occlusion followed by reperfusion and non-stroke SHAM-operated rats were used as controls. After brain injury occurred, TPO and phosphate-buffered solution were administered. Before and after stroke, an active place avoidance test was performed and data were recorded. Results indicate that administration of TPO post-stroke increases the recovery of cognitive functioning.
7 words: TPO whispers hope. Strokes yield cognitive recovery.
Christina, Jessica, Vienna (Class of 2024)